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Previous Volume 347:858-859 September 12, 2002 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: For unknown reasons, bleeding from gastrointestinal angiodysplasia in patients with severe aortic stenosis (Heyde's syndrome¹) usually ceases after aortic-valve replacement.² We have proposed that this bleeding disorder may be explained by acquired type IIA von Willebrand's syndrome,³ which is a deficiency of high-molecular-weight multimers of von Willebrand factor associated with aortic stenosis. We now report two cases of Heyde's syndrome in which abnormal von Willebrand factor–multimer profiles normalized after aortic-valve replacement.

Two women, one 65 years old and one 70 years old, underwent aortic-valve replacement for severe aortic stenosis (estimated valve area, 0.67 and 0.50 cm². . . [Full Text of this Article]

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