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Previous Volume 347:943-944 September 19, 2002 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Boyden et al. (May 16 issue)¹ describe a kindred with high bone density due to a mutation in the gene for low-density lipoprotein (LDL) receptor–related protein 5 (LRP5). Our group previously reported the finding of a mutation in LRP5 that causes an autosomal dominant syndrome of high bone mass in an extended kindred.² We found it both exciting and remarkable that another kindred with exactly the same mutation has been identified. We believe that the differences between the kindred described by Boyden et al. and our kindred are of scientific and clinical interest.

The high-bone-mass . . . [Full Text of this Article]

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