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Review Article
Current Concepts
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Volume 347:1256-1261 October 17, 2002 Number 16
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Renal Dysfunction Complicating the Treatment of Hypertension
Biff F. Palmer, M.D.

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Treatment of hypertension in patients with normal renal function does not generally cause renal dysfunction. By contrast, in patients with hypertension and chronic renal insufficiency, it is not uncommon for the serum creatinine concentration to rise as the blood pressure is lowered. This complication is likely to be encountered more often since the guidelines governing adequate blood-pressure control have been made more stringent.1,2 For many physicians, the initial response to a deterioration in renal function is to decrease the dose of antihypertensive medications. This approach is based on the belief that the kidney has been affected by an adverse event . . . [Full Text of this Article]

Renal Autoregulation

Renal Autoregulation in Chronic Hypertension

Renal Dysfunction and Specific Antihypertensive Drugs

ACE Inhibitors

Angiotensin-Receptor Blockers

Diuretics

Calcium-Channel Blockers

Beta-Blockers and Other Classes of Antihypertensive Drugs

Hyperkalemia as a Complication of Antihypertensive Therapy


Source Information

From the Department of Medicine, Division of Nephrology, University of Texas Southwestern Medical School, Dallas.

Address reprint requests to Dr. Palmer at the Department of Medicine, Division of Nephrology, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd., Dallas, TX 75390-8856, or at biff.palmer@utsouthwestern.edu.


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