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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 347:1262-1268 October 17, 2002 Number 16
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Case 32-2002 — A 58-Year-Old Man with Interstitial Pulmonary Disease
Jayaraj Rajagopol, and Eugene J. Mark

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Presentation of Case

A 58-year-old man was admitted to the hospital because of interstitial pulmonary disease.

The patient had a history of eosinophilic granuloma, which had been confirmed by right-sided open-lung biopsy 25 years earlier at another hospital and had been treated with prednisone for approximately 1 year. When the medication was discontinued, the patient resumed smoking cigarettes, so that he ultimately had more than a 25-pack-year history. Five years before admission, he had a "stroke" that impeded his speech for three or four months, with subsequent recovery. One and a half years before admission, he had a single episode of hemoptysis. A . . . [Full Text of this Article]

Differential Diagnosis

Analysis of the Recent Clinical History

Differential Diagnosis of Interstitial Lung Disease

            Connective-Tissue Disease

            Drug-Associated Disease

            Occupational Lung Disease

            Primary Interstitial Lung Disease

            Sarcoidosis

Clinical Course of Eosinophilic Granuloma

Clinical Diagnosis

Dr. Jayaraj Rajagopal's Diagnosis

Pathological Discussion

Anatomical Diagnosis

Addendum




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