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Correspondence
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Volume 347:1452-1453 October 31, 2002 Number 18
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Male Circumcision, Penile Human Papillomavirus Infection, and Cervical Cancer

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 by Castellsagué, X.
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To the Editor: Castellsagué et al. (April 11 issue)1 did not correct for several of the major known risk factors for cervical cancer: race or ethnic group, smoking, human immunodeficiency virus (HIV) infection, poor diet, long-term use of oral contraceptives, and low socioeconomic status.2 Samples for testing for human papillomavirus (HPV) were obtained by intraurethral swabbing and swabbing of the external surface of the glans and coronal sulcus. This surface is dry on circumcised penises but moist on intact penises, increasing the likelihood of detection of HPV regardless of the actual rate of infection.

In other work involving the same . . . [Full Text of this Article]




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