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Previous Volume 347:1505-1511 November 7, 2002 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 66-year-old man without diabetes has worsening high blood pressure, to 160/100 mm Hg. He has a serum creatinine level of 1.8 mg per deciliter (159 µmol per liter), an estimated glomerular filtration rate of 40 ml per minute per 1.73 m² of body-surface area, proteinuria (2+), and a total protein level of 84 mg per deciliter and a creatinine level of . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Proteinuria as a Marker of Kidney Damage

Glomerular Filtration Rate

The Clinical Plan of Action

Strict Blood-Pressure Control

Angiotensin-Converting–Enzyme Inhibitors

Areas of Uncertainty

Therapy with Antihypertensive Agents

Dietary Protein Restriction

Lipid-Lowering Agents

Cessation of Tobacco Use

Guidelines

Conclusions and Recommendations

Source Information

From the Division of Nephrology, Tufts–New England Medical Center, Boston.

Related Letters:

Nondiabetic Kidney Disease
Pitts D. B., Goto A., Levey A. S.
Extract | Full Text | PDF  
N Engl J Med 2003; 348:762-763, Feb 20, 2003. Correspondence

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