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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 347:122-130 July 11, 2002 Number 2
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Case 21-2002 — A 21-Year-Old Man with Arthritis during Treatment for Hyperthyroidism
Simon M. Helfgott, and R. Neal Smith

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Presentation of Case

A 21-year-old man was admitted to the hospital because of inflammatory lesions of the foot.

The patient had been well until 15 months before admission. At that time, while he was at home in Indonesia, he had diarrhea with fever for several weeks. A diagnosis of typhoid fever was made on the basis of a positive result on Widal's test. Several antibiotics were given, and his symptoms resolved. A few weeks later, migratory polyarthritis developed, but it subsided after one to two months. Thirteen months before admission, the patient came to this hospital while he was taking amoxicillin–clavulanate potassium.

The . . . [Full Text of this Article]

Differential Diagnosis

Infectious Diseases

Autoimmune Arthritis

Sweet's Syndrome and Behçet's Disease

Systemic Lupus Erythematosus

Antineutrophil Cytoplasmic Antibodies

Vasculitis

Propylthiouracil-Induced, ANCA-Positive Vasculitis

Clinical Diagnosis

Dr. Simon M. Helfgott's Diagnosis

Pathological Discussion

Anatomical Diagnosis


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