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Previous Volume 347:145 July 11, 2002 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Dr. Bartlett (Jan. 31 issue)¹ notes that "occasional cases [of Clostridium difficile infection] follow treatment with methotrexate or paclitaxel for cancer chemotherapy." As a medical oncologist, I encounter many cases of diarrhea associated with C. difficile infection in patients who have received broad-spectrum antibiotics because of neutropenic fever. I have yet to document a case after chemotherapy in the absence of a history of broad-spectrum antibiotic therapy. Moreover, I cannot find any well-documented cases in the literature. Is Dr. Bartlett aware of any such cases that are clearly documented?

Phillip Periman, M.D.
Harrington Cancer Center
Amarillo, TX . . . [Full Text of this Article]

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