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Correspondence
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Volume 347:145-146 July 11, 2002 Number 2
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The Antiphospholipid Syndrome

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 by Levine, J. S.
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To the Editor: In their review article, Levine et al. (March 7 issue)1 state that the prevalence of antiphospholipid antibodies increases with age and is especially high in the elderly population. This statement overlooks data on the prevalence of antiphospholipid antibodies in children. In particular, anticardiolipin antibodies can be found in a high percentage of children without any discernible disease. We observed positive values for anticardiolipin antibodies in 11.4 percent of 61 apparently healthy children at their regular preventive visits.2 In addition, Rapizzi et al. found anticardiolipin antibodies in 28 percent of 100 healthy children.3 It has generally been assumed . . . [Full Text of this Article]




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