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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 347:1783-1791 November 28, 2002 Number 22
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Case 37-2002 — A 69-Year-Old Man with Painful Cutaneous Nodules, Elevated Lipase Levels, and Abnormal Results on Abdominal Scanning
Stanley W. Ashley, and Gregory Y. Lauwers

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Presentation of Case

A 69-year-old man was admitted to the hospital because of painful cutaneous nodules, elevated lipase levels, and abnormal results on abdominal scanning.

The patient had been in stable health until 15 weeks earlier, when pain developed in his feet. Two weeks later, articular examination showed firm, nonpitting edema of both ankles and pain on compression of the pedal arches bilaterally. The urine was trace-positive for glucose. The results of laboratory tests are shown in Table 1. The levels of uric acid, total protein, albumin, globulin, aspartate aminotransferase, and alanine aminotransferase were normal. The pattern on serum protein immunoelectrophoresis was . . . [Full Text of this Article]

Differential Diagnosis

Polyarthritis and Subcutaneous Fat Necrosis

Panniculitis

Fat Necrosis and Pancreatic Disease

Pancreatic Neoplasms

Probable Diagnosis

Clinical Diagnosis

Dr. Stanley W. Ashley's Diagnosis

Pathological Discussion

Anatomical Diagnosis


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