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Correspondence
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Volume 347:1803-1804 November 28, 2002 Number 22
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Cardiac Resynchronization Therapy for Heart Failure

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 by Abraham, W. T.
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To the Editor: Abraham et al. (June 13 issue)1 report that the Multicenter InSync Randomized Clinical Evaluation (MIRACLE), a double-blind trial of resynchronization therapy in patients with end-stage heart failure, demonstrated improvements in the New York Heart Association (NYHA) functional class, quality-of-life score, and distance walked in six minutes after resynchronization therapy. The precise mechanisms underlying the benefit of biventricular pacing are not clear but appear to be related to a reduction in mitral regurgitation, an improvement in systolic function, and optimization of atrioventricular delay and resynchronization.2 Currently, the following criteria are used to identify patients who may have a . . . [Full Text of this Article]


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