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Correspondence
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Volume 347:1804-1805 November 28, 2002 Number 22
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Bites of Venomous Snakes

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 by Gold, B. S.
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To the Editor: The review by Gold et al. on bites of venomous snakes (Aug. 1 issue)1 does not mention Sutherland's pressure-immobilization technique for the first-aid treatment of neurotoxic envenomation, despite its sound experimental basis and experience of its clinical efficacy, especially in Australia.2 In controlled trials, epinephrine was effective3 and promethazine, a histamine H1-receptor blocker, was ineffective4 in preventing early anaphylactoid reactions to antivenom.

Recurrence of the effects of venom after an initial response to antivenom was demonstrated in Thailand in 1986,5 so this phenomenon should not have been an "unexpected observation" during trials of Crotalidae Polyvalent Immune . . . [Full Text of this Article]


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