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Volume 347:1822-1823 December 5, 2002 Number 23
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Atrial Fibrillation — Rhythm or Rate Control

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 by The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators
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 by Van Gelder, I. C.
-PubMed Citation
The human heart has a complex electrical system that ensures coordinated propulsion of blood under a variety of physiologic conditions. Remarkable effort is expended with each heartbeat to maintain sinus rhythm. Arrhythmias are a system failure — and none more so than atrial fibrillation. It is the most common sustained arrhythmia, and people with atrial fibrillation have a mortality rate that is twice as high as that among people with sinus rhythm. The prevalence of atrial fibrillation increases with age, from 0.5 percent among young adults to more than 6 percent among those 80 years of age or older.

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