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Volume 347:2079-2080 December 19, 2002 Number 25
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Immunosuppression and BKV Nephropathy

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by Hirsch, H. H.
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To the Editor: The study by Hirsch et al. (Aug. 15 issue)1 provides important new data in the emerging field of nephropathy associated with the polyomavirus type BK (BKV). One point, however, is not supported by their data and may be misleading. The authors repeatedly state that BKV nephropathy is associated with the use of tacrolimus or mycophenolate mofetil. They also made this assumption in an earlier report,2 and in the current study, they limited their patients to those receiving tacrolimus or mycophenolate mofetil. However, all the patients receiving mycophenolate mofetil were also receiving cyclosporine, making the determination of a . . . [Full Text of this Article]



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