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Previous Volume 347:2081-2082 December 19, 2002 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Schwartz and Vissing (Aug. 22 issue)¹ describe a patient in whom paternal inheritance of mitochondrial DNA (mtDNA) was confirmed. However, the notion of paternal inheritance of mtDNA has been raised before — in one instance, in the Journal.² In that 1983 report, 30 families were studied for transmission of mitochondrial cytopathy. Maternal inheritance occurred in the majority of cases, but three cases showed evidence of paternal transmission. Although the authors recognized this possibility, it may have been that the dominant view at that time³ prompted them to provide some alternative explanations as well, and therefore, they . . . [Full Text of this Article]

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