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Correspondence
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Volume 347:220-222 July 18, 2002 Number 3
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Chronic Urticaria and Angioedema

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 by Kaplan, A. P.
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To the Editor: In his review of chronic urticaria and angioedema (Jan. 17 issue),1 Kaplan recommends doses of fexofenadine, cetirizine, and loratadine as high as twice the doses recommended on the package labels for the control of pruritus and hives. The results of clinical trials that were submitted to the Food and Drug Administration (FDA) and that formed the basis of approval and dose recommendations for the use of these drugs in patients with chronic urticaria do not support the author's recommendation, nor do data in the published literature.

For drugs proposed for the treatment of chronic urticaria, the FDA . . . [Full Text of this Article]




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