Before the introduction of highly active antiretroviral therapyin the mid-1990s, transplantation centers were understandablyreluctant to provide scarce solid organs for patients infectedwith the human immunodeficiency virus (HIV). However, becausetreated patients can now expect to live substantially longerthan before,1,2,3 many will have end-stage organ disease longbefore they have life-threatening conditions related to HIVinfection.4 It is therefore time for the transplantation communityto readdress the safety, efficacy, and propriety of transplantingscarce organs in HIV-positive patients who need them.
In this article, we provide ethical arguments for viewing transplantationin patients with HIV infection as . . . [Full Text of this Article]
Current Practices
Ethical Considerations
Medical Considerations
Concern about Intraoperative Transmission of HIV
Other Arguments against Transplantation in HIV-Positive Patients
The Burden of Proof
Provision of "Marginal" Organs
A Call for Consistency
Related Letters:
Organ Transplantation in HIV-Infected Patients
Wright C. E., Bowers V. D., Halkic N., Bally F., Gillet M., Krishnan A., Molina A., Forman S. J., Halpern S. D., Ubel P. A., Caplan A. L.
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N Engl J Med 2002;
347:1801-1803, Nov 28, 2002.
Correspondence
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