Satish Kenchaiah, M.D., Jane C. Evans, D.Sc., Daniel Levy, M.D., Peter W.F. Wilson, M.D., Emelia J. Benjamin, M.D., Martin G. Larson, S.D., William B. Kannel, M.D., M.P.H., and Ramachandran S. Vasan, M.D.
Background Extreme obesity is recognized to be a risk factorfor heart failure. It is unclear whether overweight and lesserdegrees of obesity also pose a risk.
Methods We investigated the relation between the body-mass index(the weight in kilograms divided by the square of the heightin meters) and the incidence of heart failure among 5881 participantsin the Framingham Heart Study (mean age, 55 years; 54 percentwomen). With the use of Cox proportional-hazards models, thebody-mass index was evaluated both as a continuous variableand as a categorical variable (normal, 18.5 to 24.9; overweight,25.0 to 29.9; and obese, 30.0 or more).
Conclusions In our large, community-based sample, increasedbody-mass index was associated with an increased risk of heartfailure. Given the high prevalence of obesity in the UnitedStates, strategies to promote optimal body weight may reducethe population burden of heart failure.
Source Information
From the Framingham Heart Study, Framingham, Mass. (S.K., J.C.E., D.L., P.W.F.W., E.J.B., M.G.L., W.B.K., R.S.V.); the Section of Preventive Medicine (D.L., E.J.B., M.G.L., W.B.K., R.S.V.) and the Cardiology Section (E.J.B., R.S.V.), Boston University School of Medicine, Boston; the Cardiology Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston (D.L.); and the National Heart, Lung, and Blood Institute, Bethesda, Md. (D.L.).
Address reprint requests to Dr. Vasan at the Framingham Heart Study, 73 Mt. Wayte Ave., Suite 2, Framingham, MA 01702, or at vasan{at}fram.nhlbi.nih.gov.
Obesity and the Risk of Heart Failure
O'Brien G., Maurer M. S., Taegtmeyer H., Wilson C. R., Dart R. A., Jenny-Avital E. R., Kenchaiah S., Levy D., Vasan R. S., Massie B. M.
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N Engl J Med 2002;
347:1887-1889, Dec 5, 2002.
Correspondence
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Taegtmeyer, H., Algahim, M. F.
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Weisberg, S. P., Leibel, R., Tortoriello, D. V.
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Tominaga, H., Katoh, H., Odagiri, K., Takeuchi, Y., Kawashima, H., Saotome, M., Urushida, T., Satoh, H., Hayashi, H.
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Schocken, D. D., Benjamin, E. J., Fonarow, G. C., Krumholz, H. M., Levy, D., Mensah, G. A., Narula, J., Shor, E. S., Young, J. B., Hong, Y.
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[Abstract][Full Text]
Bahrami, H., Bluemke, D. A., Kronmal, R., Bertoni, A. G., Lloyd-Jones, D. M., Shahar, E., Szklo, M., Lima, J. A.C.
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51: 1775-1783
[Abstract][Full Text]
Abel, E. D., Litwin, S. E., Sweeney, G.
(2008). Cardiac Remodeling in Obesity. Physiol. Rev.
88: 389-419
[Abstract][Full Text]
Tanaka, T., Tsutamoto, T., Sakai, H., Nishiyama, K., Fujii, M., Yamamoto, T., Horie, M.
(2008). Effect of atrial natriuretic peptide on adiponectin in patients with heart failure. Eur J Heart Fail
10: 360-366
[Abstract][Full Text]
Lopez-Jimenez, F., Sert Kuniyoshi, F. H., Gami, A., Somers, V. K.
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133: 793-804
[Full Text]
Golbin, J. M., Somers, V. K., Caples, S. M.
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5: 200-206
[Abstract][Full Text]
Buettner, H. J., Mueller, C.
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28: 2950-2951
[Full Text]
Lee, D. S., Massaro, J. M., Wang, T. J., Kannel, W. B., Benjamin, E. J., Kenchaiah, S., Levy, D., D'Agostino, R. B. Sr, Vasan, R. S.
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[Abstract][Full Text]
Szczepaniak, L. S., Victor, R. G., Orci, L., Unger, R. H.
(2007). Forgotten but Not Gone: The Rediscovery of Fatty Heart, the Most Common Unrecognized Disease in America. Circ. Res.
101: 759-767
[Abstract][Full Text]
Whaley-Connell, A., Pavey, B. S., Chaudhary, K., Saab, G., Sowers, J. R.
(2007). Review: Renin-angiotensin-aldosterone system intervention in the cardiometabolic syndrome and cardio-renal protection. Ther Adv Cardiovasc Dis
1: 27-35
[Abstract]
Gundewar, S., Calvert, J. W., Elrod, J. W., Lefer, D. J.
(2007). Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes. Am. J. Physiol. Heart Circ. Physiol.
293: H2462-H2471
[Abstract][Full Text]
Echahidi, N., Mohty, D., Pibarot, P., Despres, J.-P., O'Hara, G., Champagne, J., Philippon, F., Daleau, P., Voisine, P., Mathieu, P.
(2007). Obesity and Metabolic Syndrome Are Independent Risk Factors for Atrial Fibrillation After Coronary Artery Bypass Graft Surgery. Circulation
116: I-213-I-219
[Abstract][Full Text]
Gomez-Ambrosi, J., Catalan, V., Ramirez, B., Rodriguez, A., Colina, I., Silva, C., Rotellar, F., Mugueta, C., Gil, M. J., Cienfuegos, J. A., Salvador, J., Fruhbeck, G.
(2007). Plasma Osteopontin Levels and Expression in Adipose Tissue Are Increased in Obesity. J. Clin. Endocrinol. Metab.
92: 3719-3727
[Abstract][Full Text]
Pinder, M. C., Duan, Z., Goodwin, J. S., Hortobagyi, G. N., Giordano, S. H.
(2007). Congestive Heart Failure in Older Women Treated With Adjuvant Anthracycline Chemotherapy for Breast Cancer. JCO
25: 3808-3815
[Abstract][Full Text]
See, R., Abdullah, S. M., McGuire, D. K., Khera, A., Patel, M. J., Lindsey, J. B., Grundy, S. M., de Lemos, J. A.
(2007). The Association of Differing Measures of Overweight and Obesity With Prevalent Atherosclerosis: The Dallas Heart Study. J Am Coll Cardiol
50: 752-759
[Abstract][Full Text]
Lopaschuk, G. D., Folmes, C. D.L., Stanley, W. C.
(2007). Cardiac Energy Metabolism in Obesity. Circ. Res.
101: 335-347
[Abstract][Full Text]
Kenchaiah, S., Pocock, S. J., Wang, D., Finn, P. V., Zornoff, L. A.M., Skali, H., Pfeffer, M. A., Yusuf, S., Swedberg, K., Michelson, E. L., Granger, C. B., McMurray, J. J.V., Solomon, S. D., for the CHARM Investigators,
(2007). Body Mass Index and Prognosis in Patients With Chronic Heart Failure: Insights From the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) Program. Circulation
116: 627-636
[Abstract][Full Text]
Ingelsson, E., Sundstrom, J., Lind, L., Riserus, U., Larsson, A., Basu, S., Arnlov, J.
(2007). Low-grade albuminuria and the incidence of heart failure in a community-based cohort of elderly men. Eur Heart J
28: 1739-1745
[Abstract][Full Text]
Tsutamoto, T., Tanaka, T., Sakai, H., Ishikawa, C., Fujii, M., Yamamoto, T., Horie, M.
(2007). Total and high molecular weight adiponectin, haemodynamics, and mortality in patients with chronic heart failure. Eur Heart J
28: 1723-1730
[Abstract][Full Text]
de Simone, G., Devereux, R. B., Chinali, M., Best, L. G., Lee, E. T., Galloway, J. M., Resnick, H. E., for the Strong Heart Study Investigators,
(2007). Prognostic Impact of Metabolic Syndrome by Different Definitions in a Population With High Prevalence of Obesity and Diabetes: The Strong Heart Study. Diabetes Care
30: 1851-1856
[Abstract][Full Text]
Papas, M. A., Alberg, A. J., Ewing, R., Helzlsouer, K. J., Gary, T. L., Klassen, A. C.
(2007). The Built Environment and Obesity. Epidemiol Rev
0: mxm009v1-
[Abstract][Full Text]
Caples, S. M., Somers, V. K.
(2007). CPAP treatment for obstructive sleep apnoea in heart failure: expectations unmet. Eur Heart J
28: 1184-1186
[Full Text]
Abe, Y., Ono, K., Kawamura, T., Wada, H., Kita, T., Shimatsu, A., Hasegawa, K.
(2007). Leptin induces elongation of cardiac myocytes and causes eccentric left ventricular dilatation with compensation. Am. J. Physiol. Heart Circ. Physiol.
292: H2387-H2396
[Abstract][Full Text]
Shimizu, H., Inoue, K., Mori, M.
(2007). The leptin-dependent and -independent melanocortin signaling system: regulation of feeding and energy expenditure. J Endocrinol
193: 1-9
[Abstract][Full Text]
Cicoira, M., Maggioni, A. P., Latini, R., Barlera, S., Carretta, E., Janosi, A., Soler, J. S., Anand, I., Cohn, J. N., Val-HeFT Investigators,
(2007). Body mass index, prognosis and mode of death in chronic heart failure: Results from the Valsartan Heart Failure Trial. Eur J Heart Fail
9: 397-402
[Abstract][Full Text]
Schmidt, D., Salahudeen, A.
(2007). The Obesity-Survival Paradox in Hemodialysis Patients: Why Do Overweight Hemodialysis Patients Live Longer?. Nutr Clin Pract
22: 11-15
[Abstract][Full Text]
De Keulenaer, G. W., Brutsaert, D. L.
(2007). Systolic and diastolic heart failure: Different phenotypes of the same disease?. Eur J Heart Fail
9: 136-143
[Abstract][Full Text]
Ingelsson, E., Lind, L., Arnlov, J., Sundstrom, J.
(2007). Sleep disturbances independently predict heart failure in overweight middle-aged men. Eur J Heart Fail
9: 184-190
[Abstract][Full Text]
Fauconnier, J., Lanner, J. T., Sultan, A., Zhang, S.-J., Katz, A., Bruton, J. D., Westerblad, H.
(2007). Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes. Cardiovasc Res
73: 376-385
[Abstract][Full Text]
Schaufelberger, M., Rosengren, A.
(2007). Heart failure in different occupational classes in Sweden. Eur Heart J
28: 212-218
[Abstract][Full Text]
Li, C., Ford, E. S, McGuire, L. C, Mokdad, A. H
(2007). Association of metabolic syndrome and insulin resistance with congestive heart failure: findings from the Third National Health and Nutrition Examination Survey. J. Epidemiol. Community Health
61: 67-73
[Abstract][Full Text]
de Krom, M., van der Schouw, Y. T., Hendriks, J., Ophoff, R. A., van Gils, C. H., Stolk, R. P., Grobbee, D. E., Adan, R.
(2007). Common Genetic Variations in CCK, Leptin, and Leptin Receptor Genes Are Associated With Specific Human Eating Patterns. Diabetes
56: 276-280
[Abstract][Full Text]
Avelar, E., Cloward, T. V., Walker, J. M., Farney, R. J., Strong, M., Pendleton, R. C., Segerson, N., Adams, T. D., Gress, R. E., Hunt, S. C., Litwin, S. E.
(2007). Left Ventricular Hypertrophy in Severe Obesity: Interactions Among Blood Pressure, Nocturnal Hypoxemia, and Body Mass. Hypertension
49: 34-39
[Abstract][Full Text]
Lamant, M., Smih, F., Harmancey, R., Philip-Couderc, P., Pathak, A., Roncalli, J., Galinier, M., Collet, X., Massabuau, P., Senard, J.-M., Rouet, P.
(2006). ApoO, a Novel Apolipoprotein, Is an Original Glycoprotein Up-regulated by Diabetes in Human Heart. J. Biol. Chem.
281: 36289-36302
[Abstract][Full Text]
Di Salvo, G., Pacileo, G., Del Giudice, E. M., Natale, F., Limongelli, G., Verrengia, M., Rea, A., Fratta, F., Castaldi, B., D'Andrea, A., Calabro, P., Miele, T., Coppola, F., Russo, M. G., Caso, P., Perrone, L., Calabro, R.
(2006). Abnormal myocardial deformation properties in obese, non-hypertensive children: an ambulatory blood pressure monitoring, standard echocardiographic, and strain rate imaging study. Eur Heart J
27: 2689-2695
[Abstract][Full Text]
Thakker, G. D., Frangogiannis, N. G., Bujak, M., Zymek, P., Gaubatz, J. W., Reddy, A. K., Taffet, G., Michael, L. H., Entman, M. L., Ballantyne, C. M.
(2006). Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction. Am. J. Physiol. Heart Circ. Physiol.
291: H2504-H2514
[Abstract][Full Text]
Lund Haheim, L., Lund Larsen, P.G., Sogaard, A.J., Holme, I.
(2006). Risk factors associated with body mass index increase in men at 28 years follow-up. QJM
99: 665-671
[Abstract][Full Text]
Ingelsson, E, Arnlov, J, Lind, L, Sundstrom, J
(2006). Metabolic syndrome and risk for heart failure in middle-aged men. Heart
92: 1409-1413
[Abstract][Full Text]
Malnick, S.D.H., Knobler, H.
(2006). The medical complications of obesity. QJM
99: 565-579
[Full Text]
Leichman, J. G, Aguilar, D., King, T. M, Vlada, A., Reyes, M., Taegtmeyer, H.
(2006). Association of plasma free fatty acids and left ventricular diastolic function in patients with clinically severe obesity.. Am. J. Clin. Nutr.
84: 336-341
[Abstract][Full Text]
Lamounier-Zepter, V., Ehrhart-Bornstein, M., Karczewski, P., Haase, H., Bornstein, S. R., Morano, I.
(2006). Human adipocytes attenuate cardiomyocyte contraction: characterization of an adipocyte-derived negative inotropic activity. FASEB J.
20: 1653-1659
[Abstract][Full Text]
Barth, M. M., Jenson, C. E.
(2006). Postoperative nursing care of gastric bypass patients.. Am J Crit Care
15: 378-387
[Abstract][Full Text]
Ommen, E. S., Winston, J. A., Murphy, B.
(2006). Medical Risks in Living Kidney Donors: Absence of Proof Is Not Proof of Absence. CJASN
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[Abstract][Full Text]
Gondoni, L A, Liuzzi, A, Titon, A M, Taronna, O, Nibbio, F, Ferrari, P, Leonetti, G
(2006). A simple tool to predict exercise capacity of obese patients with ischaemic heart disease. Heart
92: 899-904
[Abstract][Full Text]
Poirier, P., Giles, T. D., Bray, G. A., Hong, Y., Stern, J. S., Pi-Sunyer, F. X., Eckel, R. H.
(2006). Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss.. Arterioscler. Thromb. Vasc. Bio.
26: 968-976
[Abstract][Full Text]
Butler, J., Rodondi, N., Zhu, Y., Figaro, K., Fazio, S., Vaughan, D. E., Satterfield, S., Newman, A. B., Goodpaster, B., Bauer, D. C., Holvoet, P., Harris, T. B., de Rekeneire, N., Rubin, S., Ding, J., Kritchevsky, S. B., for the Health ABC Study,
(2006). Metabolic Syndrome and the Risk of Cardiovascular Disease in Older Adults. J Am Coll Cardiol
47: 1595-1602
[Abstract][Full Text]
Kang, X., Shaw, L. J., Hayes, S. W., Hachamovitch, R., Abidov, A., Cohen, I., Friedman, J. D., Thomson, L. E.J., Polk, D., Germano, G., Berman, D. S.
(2006). Impact of Body Mass Index on Cardiac Mortality in Patients With Known or Suspected Coronary Artery Disease Undergoing Myocardial Perfusion Single-Photon Emission Computed Tomography. J Am Coll Cardiol
47: 1418-1426
[Abstract][Full Text]
McGavock, J. M., Victor, R. G., Unger, R. H., Szczepaniak, L. S.
(2006). Adiposity of the Heart*, Revisited. ANN INTERN MED
144: 517-524
[Abstract][Full Text]
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