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Volume 347:368-370 August 1, 2002 Number 5
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Amiodarone versus Lidocaine for Shock-Resistant Ventricular Fibrillation

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by Dorian, P.
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To the Editor: Dorian and colleagues (March 21 issue)1 report increased rates of survival to hospital admission among patients treated with amiodarone for out-of-hospital ventricular fibrillation. Although their conclusion is consistent with their data and is in accordance with those reported previously by Kudenchuk and coworkers,2 the questions of cost versus benefit and of reasonable outcome measures are raised. The results presented by Dorian et al. suggest that treatment of 100 patients could result in 10 additional hospital admissions but survival to discharge from the hospital for only 1 additional patient, without proven neurologic recovery.

In both studies, the use . . . [Full Text of this Article]



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