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Previous Volume 347:621-622 August 22, 2002 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Angioedema is a nonitchy, pale swelling of subcutaneous or submucosal tissue that tends to recur chronically and can become life-threatening if the swelling occurs in the upper airways or can be very painful if it occurs in the gastrointestinal tract. Angioedema presenting together with urticaria¹ usually responds well to antihistamines and corticosteroids, whereas angioedema without urticaria is frequently resistant to such therapy but may respond to a C1 esterase inhibitor, tranexamic acid, or both² — therapies that can reduce bradykinin generation. These findings raise the question of whether bradykinin mediates angioedema.

We measured plasma bradykinin in patients . . . [Full Text of this Article]

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