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Editorial
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Volume 347:684-686 August 29, 2002 Number 9
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Nephrogenic Adenomas as Renal Tubular Outposts

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 by Mazal, P. R.
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Nephrogenic adenomas, which are rare intraurothelial lesions that occur in the bladder, ureter, or urethra, most often present with hematuria or discomfort on voiding. Some patients have no symptoms at all, but occasionally, obstruction develops. These lesions are generally discovered long after an apparent urologic insult or the initiation of immunosuppression, and their origin is enigmatic. The growths consist of tubule-like microstructures, but whether these lesions originate from mesothelial rests, represent squamous metaplasia, or derive from exfoliated renal tubular cells is unclear. In this issue of the Journal, Mazal et al.1 present compelling evidence that these unusual adenomas originate from . . . [Full Text of this Article]


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