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Previous Volume 348:1067-1069 March 13, 2003 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Delayed-onset heparin-induced thrombocytopenia, a newly described syndrome of immune-mediated thrombocytopenia that begins several days after heparin therapy has been discontinued,^1,2 is caused by IgG antibodies that are reactive against platelet factor 4–heparin complexes that activate platelets even in the absence of pharmacologic heparin.¹ The minimal amount of heparin required to initiate this syndrome is unknown.

We describe a 44-year-old woman who received a single injection of unfractionated heparin (5000 units) before undergoing Roux-en-Y gastric bypass for obesity. Previous exposure to heparin was unlikely, since she did not have a history of thrombosis or hospitalizations (other than two . . . [Full Text of this Article]

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