The ethical justification for clinical research as currentlyconducted has been questioned on the grounds that physiciansdo not make a strict and unequivocal distinction for their patientsbetween clinical research and clinical care, and their patientsmay therefore participate in clinical studies with the falseimpression that they are being cared for to the best of theirphysicians' ability.1 This issue raises difficult and controversialquestions about the intentions, goals, and responsibilitiesof clinical researchers, as evidenced by the numerous editorialsand articles on the subject that have appeared in the Journalin recent decades.2,3,4,5,6 These are certainly timely . . . [Full Text of this Article]
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From the Divisions of Hematology–Oncology (S.M.G.) and Endocrinology, Diabetes, and Metabolism (W.T.C.), University of Vermont School of Medicine, Burlington.
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