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Previous Volume 348:1407 April 3, 2003 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We concur with Dr. Tournier-Lasserve (Nov. 21 issue)¹ that linkage methods for genetic studies of stroke are hampered by difficulties in collecting pedigrees with several affected members.² There are ongoing studies that should allow this goal to be accomplished. The National Institute of Neurological Disorders and Stroke is supporting a 50-center study in North America known as the Siblings with Ischemic Stroke Study.³ Though not designed to assemble extended, multiplex families as was done in Iceland, this study will assemble 300 sibling pairs and trios for the purpose of performing a genome-wide scan for loci that confer . . . [Full Text of this Article]

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