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Previous Volume 348:1411-1412 April 3, 2003 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In 1907, George Whipple performed an autopsy on a 36-year-old patient and described unique findings characterizing the disease that now bears his name. "Foamy macrophages" in lymph nodes and the lamina propria of the small intestine are the hallmarks of Whipple's disease. In addition, Whipple described a "number of rod-shaped organisms resembling in form the tubercle bacillus" in the vacuoles of the foamy cells.¹ The role of a bacterium in the disease was suggested but not yet acknowledged. By 1949, the contents of the foamy macrophages were shown to be positive on periodic acid–Schiff (PAS) staining, and . . . [Full Text of this Article]

This article has been cited by other articles:

• Fenollar, F., Puechal, X., Raoult, D. (2007). Whipple's Disease. NEJM 356: 55-66 [Full Text]