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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 348:1464-1476 April 10, 2003 Number 15
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Case 11-2003 — A 14-Year-Old Boy with Ulcerative Colitis, Primary Sclerosing Cholangitis, and Partial Duodenal Obstruction
Albert M. Ross, IV, M.D., Sudha A. Anupindi, M.D., and Ulysses J. Balis, M.D.

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Presentation of Case

A 14-year-old boy with a history of ulcerative colitis was admitted to the hospital because of vomiting and abdominal pain.

Ulcerative colitis had been diagnosed at the age of three years by colonoscopic examination after a barium-enema examination had revealed no abnormalities. In subsequent years, progression of the disease was well controlled with the administration of mesalamine and short courses of an adrenocorticosteroid medication for flares; hospital admission was not required. The patient lived with his parents, two siblings, and a healthy dog. There was no family history of gastrointestinal or autoimmune diseases.

First Admission

Fourteen months before the current admission, abdominal . . . [Full Text of this Article]

Second Admission

Third Admission

Fourth Admission

Fifth Admission

Sixth Admission

Seventh Admission

Eighth Admission

Ninth admission

10th Admission

11th Admission

Differential Diagnosis

Primary Sclerosing Cholangitis

Acalculous Cholecystitis

Recurrent Ascending Cholangitis

Chronic Pancreatitis

Duodenal Stricture

Summary

Clinical Diagnosis

Dr. Albert M. Ross's Diagnoses

Pathological Discussion

Anatomical Diagnosis


Source Information

From the Department of Pediatrics, Hasbro Children's Hospital, and the Department of Pediatrics, Brown University Medical School — both in Providence, R.I. (A.M.R.); and the Departments of Radiology (S.A.A.) and Pathology (U.J.B.), Massachusetts General Hospital and Harvard Medical School, Boston.


Related Letters:

Case 11-2003: Ulcerative Colitis and Primary Sclerosing Cholangitis in a 14-Year-Old Boy
Drewe E., Zaitoun A. M., Walker D. A., Mukherjee S.
Extract | Full Text | PDF  
N Engl J Med 2003; 349:1482, Oct 9, 2003. Correspondence

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