Venous thromboembolism encompasses deep venous thrombosis andpulmonary embolism, which represent different manifestationsof the same disease process. Indeed, most patients in whom symptomsof either condition develop will simultaneously have overt orsubclinical evidence of the other. Our understanding of thecauses and natural history of venous thromboembolism has undergoneconsiderable evolution in recent years, influencing the clinicalapproach to diagnosis and treatment. It is now recognized thatvenous thromboembolism is a chronic disease. Almost one thirdof patients have a recurrence within eight years after the initialevent.1 Furthermore, venous thromboembolism is at least in parta systemic . . . [Full Text of this Article]
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From the University of Pennsylvania School of Medicine, Philadelphia.
This article was published at www.nejm.org on February 24, 2003.
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