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Editorial
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Volume 348:1478-1480 April 10, 2003 Number 15
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Warfarin for Venous Thromboembolism — Walking the Dosing Tightrope
Andrew I. Schafer, M.D.

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 by Ridker, P. M
-PubMed Citation
Venous thromboembolism encompasses deep venous thrombosis and pulmonary embolism, which represent different manifestations of the same disease process. Indeed, most patients in whom symptoms of either condition develop will simultaneously have overt or subclinical evidence of the other. Our understanding of the causes and natural history of venous thromboembolism has undergone considerable evolution in recent years, influencing the clinical approach to diagnosis and treatment. It is now recognized that venous thromboembolism is a chronic disease. Almost one third of patients have a recurrence within eight years after the initial event.1 Furthermore, venous thromboembolism is at least in part a systemic . . . [Full Text of this Article]


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From the University of Pennsylvania School of Medicine, Philadelphia.

This article was published at www.nejm.org on February 24, 2003.


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