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A 28-year-old patient was admitted to the hospital with mild pleuritic chest pain. A posterior–anterior chest radiograph showed bilateral diffuse, nodular ("sandstorm-like") calcifications in both lungs, predominantly in the middle zones (Panel A). A high-resolution computed tomographic scan demonstrated multiple bilateral diffuse micronodular, calcific, and ground-glass opacities throughout both lungs (Panel B). On transbronchial biopsy, the diagnosis of massive parenchymal and alveolar calcification was confirmed. Abdominal ultrasonography revealed medullary nephrocalcinosis. On the basis of these findings, the diagnosis of pulmonary alveolar microlithiasis with concomitant idiopathic medullary nephrocalcinosis was established. Pulmonary alveolar microlithiasis is a rare and slowly progressive disease; the . . . [Full Text of this Article] |
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