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Volume 348:1623-1624 April 24, 2003 Number 17
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Obesity and Mortality from Cancer
Hans-Olov Adami, M.D., and Dimitrios Trichopoulos, M.D.

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 by Calle, E. E.
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Laboratory investigators have long known that animals in which energy intake is reduced to about 60 percent of the intake of animals that are fed as much as they want have a considerably lower incidence of cancer than the control animals. This finding apparently holds true for viral, chemical, and even spontaneous carcinogenesis. Evidence from studies in humans has been largely compatible with these laboratory findings and is applicable to a wide spectrum of sites and types of tumors. Yet this evidence has not stimulated the development of programs to prevent cancer by weight control.

There are several reasons for . . . [Full Text of this Article]


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From the Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden (H.-O.A.), and the Department of Epidemiology, Harvard School of Public Health, Boston (D.T.).


Related Letters:

Obesity and Cancer
Deutsch M. E., Flegal K. M., Williamson D. F., Graubard B. I., Frankel P. H., Gaesser G. A., Smith J. A., Calle E. E., Rodriguez C., Thun M. J.
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N Engl J Med 2003; 349:502-504, Jul 31, 2003. Correspondence

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