This Journal feature begins with a case vignette highlightinga common clinical problem. Evidence supporting various strategiesis then presented, followed by a review of formal guidelines,when they exist. The article ends with the authors' clinicalrecommendations.
A 44-year-old woman who is a new patient has no known currenthealth problems and no family history of breast or ovarian cancer.Eighteen months ago, she had a normal screening mammogram. Sherecently read that mammograms may not help to prevent deathfrom breast cancer and that "the patient should decide." Butshe does not think she knows enough. She worries . . . [Full Text of this Article]
The Clinical Problem
Strategies, Evidence, and Areas of Uncertainty
The Risk of Development of and Death from Breast Cancer
Mammography and Mortality from Breast Cancer
Women in Their 40s
Mammography in Women Older than 70 Years of Age
Risks Associated with Mammography
False Positive Mammograms
Possible Overdiagnosis Ductal Carcinoma in Situ
Other Risks
Guidelines
Conclusions and Recommendations
General Conclusions
Specific Recommendations
Source Information
From the Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston (S.W.F.); and the Department of Medicine, University of Washington, Seattle (J.G.E.).
Address reprint requests to Dr. Fletcher at the Department of Ambulatory Care and Prevention, 6th Fl., 133 Brookline Ave., Boston, MA 02215.
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