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Previous Volume 348:1928-1931 May 8, 2003 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We welcome the article by Nathoe and colleagues (Jan. 30 issue).¹ In its infancy, off-pump coronary-artery bypass was mostly used in high-risk patients,² with observed reductions in morbidity and mortality.³ Cardiopulmonary bypass has two main disadvantages: a systemic inflammatory response syndrome and microembolization, which leads to multiorgan dysfunction.⁴ It seems rational that all patients, both those at high risk and those at low risk, would benefit from a technique that avoids the use of cardiopulmonary bypass. The study by Nathoe et al. did not show a significant difference in cardiac outcomes between coronary-artery bypass grafting with cardiopulmonary . . . [Full Text of this Article]

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