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Correspondence
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Volume 348:171-174 January 9, 2003 Number 2
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Endotoxin and Asthma

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 by Weiss, S. T.
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 by Braun-Fahrländer, C.
-PubMed Citation
To the Editor: Investigators in the Allergy and Endotoxin (ALEX) Study have shown previously that exposure to stables and farm milk during the first year of life protects against asthma and hay fever at 6 to 13 years of age, plausibly through exposure to microbial components.1 Braun-Fahrländer et al. (Sept. 19 issue)2 substantiate this proposition by showing that current endotoxin levels in children's mattresses were inversely associated with the occurrence of hay fever and atopic asthma and that leukocytes from children with high levels of exposure to endotoxin produced less of the cytokines tumor necrosis factor {alpha}, interferon-{gamma}, interleukin-10, . . . [Full Text of this Article]


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