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Previous Volume 348:2157-2159 May 22, 2003 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The review article by Cooper and Stewart on corticosteroid insufficiency in acutely ill patients (Feb. 20 issue)¹ makes recommendations concerning the diagnosis and treatment of adrenal insufficiency in patients with septic shock. Although base-line cortisol and corticotropin testing may help to identify patients with an increased risk of death,² it is still unclear how to define adrenal insufficiency.^2,3 Various base-line cortisol levels, changes in cortisol levels, or both have been used,³ and none can as yet identify the subgroups of patients who have adrenal insufficiency and who benefit from the use of corticosteroids.^3,4

The use of hydrocortisone . . . [Full Text of this Article]

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