Ambulatory blood-pressure monitoring provides automated measurementsof brachial-artery pressure over a 24-hour period while patientsare engaging in their usual activities. This method has beenused for more than 30 years in clinical research on hypertension.Initially, it was performed in cardiovascular research unitswith the use of direct intraarterial recordings during physicalactivity, work, rest, and sleep. These studies demonstratedthat blood pressure has a highly reproducible circadian profile,with higher values when the patient is awake and mentally andphysically active, much lower values during rest and sleep,and an early-morning surge lasting three to five hours during. . . [Full Text of this Article]
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From the Division of Hypertension and Clinical Pharmacology, University of Connecticut School of Medicine, Farmington.
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