To the Editor: A trial of vaccination against Lyme disease providedan opportunity for us to determine the relative frequenciesof the presenting manifestations of Lyme disease and the outcomesof treatment in a large population.1 Our goal was to identifyall cases of Borrelia burgdorferi infection that occurred amongthe 10,936 participants in 10 states where the infection isendemic during the 20-month study period.
Of the 1917 participants who were evaluated for Lyme disease,269 met the prospectively defined criteria for definite, possible,or asymptomatic infection.1 After completion of the study, posthoc analyses were performed for patients . . . [Full Text of this Article]
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