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Previous Volume 348:439-446 January 30, 2003 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Perspective by Schraeder, T. L. Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear PubMed Citation

The Department of Health and Human Services is finalizing plans for a U.S. vaccination program against smallpox. As more vaccinia virus vaccine has become available, the debate over how many persons to vaccinate has centered on two issues: the safety of the live vaccine and the transmissibility of vaccinia virus from a recently vaccinated person to a susceptible host.

The issue of safety has received substantial attention, given that a predictable number of adverse events will occur among vaccine recipients. Furthermore, an extensive literature has established credible estimates of the complication rates.^1,2,3,4 The risk of secondary transmission, however, is discussed . . . [Full Text of this Article]

Nosocomial Spread

Spread within Families

Other Transmission

Implications for Vaccination Policy

Source Information

From the Infectious Disease Service, Memorial Sloan-Kettering Cancer Center, New York.

This article was published at www.nejm.org on December 19, 2002.

Address reprint requests to Dr. Sepkowitz at the Infectious Disease Service, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021, or at sepkowik@mskcc.org.

Related Letters:

Smallpox and Smallpox Vaccination
Letai A. G., Snyder K. M., Fett J. D., Worthington M. G., Ross J. J., Neff J. M., Lane J. M., Fulginiti V. A., Milton D. K., Bozzette S. A., Boer R., Mack T., Sepkowitz K. A.
Extract | Full Text | PDF  
N Engl J Med 2003; 348:1920-1925, May 8, 2003. Correspondence

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