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Volume 348:487-488 February 6, 2003 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Cocaine use has been associated with both acute and chronic cardiovascular diseases. These include acute myocardial infarction, myocardial ischemia (both silent ischemia and ischemia associated with angina), acceleration of the development of atherosclerosis, myocarditis, cardiomyopathy (both dilated and hypertrophic), arrhythmias, hypertension, aortic dissection, and endocarditis. An estimated 25 million Americans have tried cocaine at least once.

Cocaine may be administered by smoking, nasal insufflation, or intravenous injection; cardiac events can follow administration by any of these routes. Cocaine is rapidly absorbed through the respiratory tract; smoking cocaine delivers the substance to the circulation within seconds to minutes. After nasal insufflation . . . [Full Text of this Article]

Source Information

From the Heart Institute, Good Samaritan Hospital, and the Division of Cardiovascular Medicine, Keck School of Medicine, University of Southern California — both in Los Angeles (R.A.K.); and the Department of Cardiology, Marshfield Clinic, Marshfield, Wis. (S.H.R.).

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