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Volume 348:661-663 February 13, 2003 Number 7
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Digoxin for the Treatment of Heart Failure

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 by Eichhorn, E. J.
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 by Rathore, S. S.
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To the Editor: The report by Rathore et al. (Oct. 31 issue)1 emphasizes differences according to sex in the outcomes of digoxin therapy in patients with congestive heart failure. Their post hoc analysis showed that outcomes differed between men and women. With respect to the characteristics of the patients, there were striking differences between men and women in the causes of congestive heart failure. Women more often had cardiomegaly, severe heart failure, diabetes, and idiopathic heart failure; men more often had ischemic heart failure and heart failure due to prior myocardial infarction. Digoxin may be a useful treatment for some . . . [Full Text of this Article]


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