This Journal feature begins with a case vignette highlightinga common clinical problem. Evidence supporting various strategiesis then presented, followed by a review of formal guidelines,when they exist. The article ends with the authors' clinicalrecommendations.
A 29-year-old woman with a history of mitral stenosis who hasa St. Jude Medical mitral-valve prosthesis presents for evaluationbefore attempting to conceive. She is concerned about the risksthat pregnancy will confer on her and her child. How shouldshe be evaluated and followed?
The Clinical Problem
Valvular heart disease in young women is most commonly due torheumatic heart disease, congenital abnormalities, . . . [Full Text of this Article]
Cardiovascular Physiology of Pregnancy
Consequences of Valvular Heart Disease during Pregnancy
Strategies and Evidence
Evaluation
Pharmacologic Treatment
Specific Valvular Lesions
Mitral Stenosis
Mitral Regurgitation
Aortic Stenosis
Aortic Regurgitation
Prosthetic Heart Valves
Areas of Uncertainty
Guidelines
Summary and Recommendations
Source Information
From the University of Texas Southwestern Medical Center, Dallas.
2006 WRITING COMMITTEE MEMBERS, , Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C. Jr, Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O'Gara, P. T., O'Rourke, R. A., Otto, C. M., Shah, P. M., Shanewise, J. S.
(2008). 2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): Endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation
118: e523-e661
[Full Text]
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C. Jr, Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O'Gara, P. T., O'Rourke, R. A., Otto, C. M., Shah, P. M., Shanewise, J. S., Nishimura, R. A., Carabello, B. A., Faxon, D. P., Freed, M. D., Lytle, B. W., O'Gara, P. T., O'Rourke, R. A., Shah, P. M.
(2008). 2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease) Endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol
52: e1-e142
[Full Text]
Stout, K. K, Otto, C. M
(2007). Pregnancy in women with valvular heart disease. Heart
93: 552-558
[Abstract][Full Text]
Stout, K. K., Otto, C. M.
(2007). Indications for Aortic Valve Replacement in Aortic Stenosis. J Intensive Care Med
22: 14-25
[Abstract]
Stoneham, A. E., Graham, J., Rozanski, E. A., Rush, J. E.
(2006). Pregnancy-associated congestive heart failure in a cat.. Journal of the American Animal Hospital Association
42: 457-461
[Abstract][Full Text]
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C. Jr, Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O'Gara, P. T., O'Rourke, R. A., Otto, C. M., Shah, P. M., Shanewise, J. S., Smith, S. C. Jr, Jacobs, A. K., Adams, C. D., Anderson, J. L., Antman, E. M., Faxon, D. P., Fuster, V., Halperin, J. L., Hiratzka, L. F., Hunt, S. A., Lytle, B. W., Nishimura, R., Page, R. L., Riegel, B.
(2006). ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease) Developed in Collaboration With the Society of Cardiovascular Anesthesiologists Endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol
48: e1-e148
[Full Text]
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C. Jr, Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O'Gara, P. T., O'Rourke, R. A., Otto, C. M., Shah, P. M., Shanewise, J. S., Smith, S. C. Jr, Jacobs, A. K., Adams, C. D., Anderson, J. L., Antman, E. M., Faxon, D. P., Fuster, V., Halperin, J. L., Hiratzka, L. F., Hunt, S. A., Lytle, B. W., Nishimura, R., Page, R. L., Riegel, B.
(2006). ACC/AHA 2006 Practice Guidelines for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease) Developed in Collaboration With the Society of Cardiovascular Anesthesiologists Endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol
48: 598-675
[Full Text]
Ruiz, C. E., Iemura, M., Medie, S., Varga, P., Van Alstine, W. G., Mack, S., Deligio, A., Fearnot, N., Beier, U. H., Pavcnik, D., Hijazi, Z. M., Kiupel, M.
(2005). Transcatheter placement of a low-profile biodegradable pulmonary valve made of small intestinal submucosa: A long-term study in a swine model. J. Thorac. Cardiovasc. Surg.
130: 477-484
[Abstract][Full Text]
Child, J. S.
(2004). Fallot's tetralogy and pregnancy: Prognostication and prophesy. J Am Coll Cardiol
44: 181-183
[Full Text]
Arafeh, J., El-Sayed, Y. Y.
(2004). Cardiac Disease in Pregnancy. NeoReviews
5: e232-e239
[Full Text]
Mulder, B. J.M., Bleker, O. P.
(2003). Valvular Heart Disease in Pregnancy. NEJM
349: 1387-1387
[Full Text]
Schulman, S.
(2003). Care of Patients Receiving Long-Term Anticoagulant Therapy. NEJM
349: 675-683
[Full Text]