Two decades after the presence of anticardiolipin antibodiesand a syndrome of spontaneous thrombosis and fetal death werelinked,1 and after the publication of approximately 3500 reportsin which the term "antiphospholipid syndrome" has been used,we still lack scientifically robust, evidence-based rules forthe treatment of the antiphospholipid syndrome. This failureis due in part to a lack of well-designed prospective studiesand in part to the clinical complexity of the syndrome. Thecomplexity stems in part from the fact that the antiphospholipidsyndrome actually comprises two syndromes, one that is not associatedwith another illness (primary antiphospholipid syndrome), . . . [Full Text of this Article]
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From the Hospital for Special Surgery, Joan and Sanford Weill College of Medicine of Cornell University, New York.
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