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Volume 349:1185-1186 September 18, 2003 Number 12
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Use of MRI to Detect Lymph-Node Metastases in Prostate Cancer

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 by Harisinghani, M. G.
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To the Editor: The results reported by Harisinghani et al. (June 19 issue)1 may have been influenced by the limited dissection of lymph nodes in their study. In most patients, only obturator nodes were dissected, yielding 334 nodes from 80 patients — an average of 4.2 nodes per patient. In contrast, one study of an extended node dissection in a similar group of patients with prostate cancer2 found a median of 21 nodes per patient in the histologic specimens. Of the patients with positive nodes, 13 percent had positive internal iliac nodes only,2 which would have been missed by limited . . . [Full Text of this Article]


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