This Journal feature begins with a case vignette highlightinga common clinical problem. Evidence supporting various strategiesis then presented, followed by a review of formal guidelines,when they exist. The article ends with the authors' clinicalrecommendations.
An otherwise healthy 51-year-old woman presents to her physicianwith pleuritic right posterior chest pain, without dyspnea orhemoptysis. Her temperature is 38.2°C, and her pulse is102 beats per minute. Physical examination discloses a pleuralfriction rub over the posterior right hemithorax but is otherwiseunremarkable. A chest radiograph is normal. She is treated withan antiinflammatory agent for presumed viral . . . [Full Text of this Article]
The Clinical Problem
Strategies and Evidence
Clinical Diagnosis
D-Dimer Testing
VentilationPerfusion Scanning
Computed Tomography
Evaluation of the Leg Veins
Conventional Pulmonary Angiography
Approaches to Testing
High Clinical Probability of Pulmonary Embolism
Low Clinical Probability of Pulmonary Embolism
Intermediate Clinical Probability of Pulmonary Embolism
Special Circumstances
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Division of Pulmonary and Critical Care Medicine, University of California, San Diego, Medical Center, San Diego (P.F.F.); and the Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, N.C. (V.F.T.).
Address reprint requests to Dr. Fedullo at the Division of Pulmonary and Critical Care Medicine, University of California, San Diego, Medical Center, 9300 Campus Point Dr., MC 7381, La Jolla, CA 92037-1300, or at pfedullo@uscb.edu.
Related Letters:
Suspected Pulmonary Embolism
Ranji S. R., Shojania K. G., Rosenberger P., Shernan S. K., Eltzschig H. K., Gaenzer H., Fedullo P. F., Tapson V. F.
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N Engl J Med 2004;
350:82-84, Jan 1, 2004.
Correspondence
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