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Previous Volume 349:1479-1480 October 9, 2003 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Regarding the article by Selzer et al. on the adverse effect of nitrous oxide (July 3 issue),¹ I would like to point out that, in 1978, my colleagues and I showed that nitrous oxide inactivated vitamin B₁₂ in vivo.² My colleague John Amess, as a member of the department of the late David Mollin, observed megaloblastic erythropoiesis in a patient who had received nitrous oxide in 1975 after being injured in a train accident at Moorgate Station on the edge of the City of London. We then conducted a prospective trial in which we showed, using the . . . [Full Text of this Article]

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