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Volume 349:1968-1971 November 13, 2003 Number 20
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Sentinel-Node Biopsy in Breast Cancer

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 by Krag, D.
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 by Veronesi, U.
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To the Editor: Veronesi and colleagues (Aug. 7 issue)1 report a sensitivity of 91.2 percent with the use of a meticulous frozen-section method in which at least 60 sections per node are prepared and an immunohistochemical method is used for the detection of metastases in patients with breast cancer. This time-consuming and expensive method is far superior to the conventional method used for the remainder of the axillary nodes for the detection of metastases. Three to six sections were obtained from each of the remaining axillary nodes.

It is a well-known fact that increasing the number of sections improves the . . . [Full Text of this Article]




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