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Volume 349:2068-2071 November 20, 2003 Number 21
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Bisphosphonates in Children with Bone Diseases

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 by Marini, J. C.
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 by Whyte, M. P.
-PubMed Citation
To the Editor: In her Perspective article on bisphosphonates in children with bone diseases (July 31 issue),1 Dr. Marini comments that "treatment with bisphosphonates from infancy does not relieve the short stature of children with osteogenesis imperfecta." It is important to note that the use of bisphosphonates for the treatment of infants with osteogenesis imperfecta has only recently been attempted,2 and the patients who have been treated have not yet reached their final height. Thus, it is not feasible to predict the final effects of the treatment. In the meantime, bisphosphonate-treated children with osteogenesis imperfecta appear to be growing faster . . . [Full Text of this Article]




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