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Correspondence
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Volume 349:2170-2171 November 27, 2003 Number 22
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Genomic Medicine

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 by Guttmacher, A. E.
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To the Editor: In their editorial (Sept. 4 issue),1 Guttmacher and Collins provide a conventional and optimistic overview of the effects of genomics on clinical practice. Absent from their discussion is mention of the most common current use of genetics in clinical practice: negative eugenics. Testing for chromosomal disorders is routine in obstetrics and fertility medicine. The example of Tay–Sachs disease demonstrates that voluntary screening of the population and genetic counseling can have a substantial effect on the incidence of disease.2 As the novelist Josef Skvorecky has written, "the past shows the potential of the future."3 Increasing knowledge of genetic . . . [Full Text of this Article]


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