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Previous Volume 349:2360-2361 December 11, 2003 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Hylek and colleagues (Sept. 11 issue)¹ report that in patients with nonvalvular atrial fibrillation who were admitted with stroke, an international normalized ratio (INR) of less than 2.0 was associated with a greater severity of stroke and higher mortality than an INR of 2.0 or greater. The median of all INR values during the six months before the stroke was the same in the two INR groups. Taken together, these data indicate that thrombus formation is triggered even if anticoagulation is adequate and that thrombi grow larger if the INR is less than 2.0. These notions suggest . . . [Full Text of this Article]

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