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Previous Volume 349:2364 December 11, 2003 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In their excellent review of the molecular epidemiology of tuberculosis, Barnes and Cave (Sept. 18 issue)¹ recommend that the Centers for Disease Control and Prevention (CDC) support newer, more rapid genotyping tests. In fact, the CDC is doing just that. This winter, two genotyping laboratories will use two polymerase-chain-reaction–based methods — mycobacterial-interspersed-repetitive-units (MIRU) analysis² and spoligotyping³ — for primary genotyping of Mycobacterium tuberculosis isolates. The laboratories will have the capacity to analyze isolates from every patient with culture-positive tuberculosis in the United States and will report results in less than two weeks. In combination, these methods are . . . [Full Text of this Article]

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