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Volume 349:500-502 July 31, 2003 Number 5
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Intellectual Impairment and Blood Lead Levels

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 by Rogan, W. J.
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 by Canfield, R. L.
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 by Selevan, S. G.
-PubMed Citation
To the Editor: In the light of the report on intellectual impairment and blood lead levels by Canfield et al. (April 17 issue),1 we reanalyzed data from our prospective cohort study,2 focusing on 48 children whose blood lead levels never exceeded 10 µg per deciliter at birth or at 6, 12, 18, 24, 57, or 120 months. The IQ at 120 months was inversely related to the lead level at 24 months with adjustment for covariates (P=0.03). Nonparametric smoothing analyses suggested that the inverse association persisted at blood lead levels below 5 µg per deciliter.3 The blood lead coefficient (–1.56) . . . [Full Text of this Article]


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