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Case Records of the Massachusetts General Hospital
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Volume 349:691-700 August 14, 2003 Number 7
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Case 25-2003 — A Newborn Boy with Petechiae and Thrombocytopenia
John F. Modlin, M.D., P. Ellen Grant, M.D., Robert S. Makar, M.D., Ph.D., Drucilla J. Roberts, M.D., and Kalpathy S. Krishnamoorthy, M.D., M.B., B.S.

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Presentation of Case

A newborn boy was admitted to a special-care nursery because of petechiae and thrombocytopenia.

The boy had been delivered at this hospital at 39 weeks' gestation to a 32-year-old woman who had had premature rupture of the membranes 16 hours before delivery. A single dose of penicillin was administered to the mother before vacuum-assisted delivery. The Apgar score was 9 at one minute and at five minutes. A diffuse petechial rash, most prominent on the face and trunk, was noted at delivery, and the baby was transferred to a newborn nursery.

The mother had never smoked, and she had not . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnosis

Dr. John F. Modlin's Diagnosis

Diagnostic Discussion

Discussion of Management

Pathological Diagnosis


Source Information

From the Departments of Pediatrics and Medicine, Dartmouth–Hitchcock Medical Center and Dartmouth Medical School, Lebanon, N.H. (J.F.M.); the Departments of Radiology (P.E.G.), Pathology (R.S.M., D.J.R.), and Pediatrics (K.S.K.), Massachusetts General Hospital and Harvard Medical School.


Related Letters:

Case 25-2003: Congenital Cytomegalovirus Infection
Barton L. L., Modlin J. F.
Extract | Full Text | PDF  
N Engl J Med 2003; 349:1575-1576, Oct 16, 2003. Correspondence

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